产品货号：
Z18557
中文名称：
IL18抗体
英文名称：
Anti-IL18 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IL18 Antibody |
| 指标别名 | Iboctadekin;IFN gamma inducing factor;IGIF;IL 1 gamma;IL 18;IL 1g;IL18;IL-18;IL1F4;Interleukin 1 gamma;Interleukin 18;Mature IL18;pre IL18;Pre-IL18 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,WB |
| 基因名称 | IL18 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Polypeptide |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Interleukin-18 also known as IL18 is a protein which in humans is encoded by the IL18 gene.The protein encoded by this gene is a proinflammatory cytokine.IL-18 is a cytokine produced by macrophages and other cells that belongs to the IL-1 superfamily.IL-18 works by binding to the interleukin-18 receptor,and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide(LPS).After stimulation with IL-18,natural killer(NK) cells and certain T cells release another important cytokine called interferon-gamma(IFN-gamma) or type II interferon that plays an important role in activating the macrophages or other cells.The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production,and enhance IgG2a production in B cells.IL-18 binding protein(IL18BP) can specifically interact with this cytokine,and thus negatively regulate its biological activity.The human interleukin 18 gene IL18 maps to 11q22.2-q22.3,closely linked to the DRD2 gene locus and distinct from mapped IDDM loci. |
| Uniprot ID | Q14116 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | interleukin 18(interferon-gamma-inducing factor) |
| 蛋白名全称 | Interleukin-18 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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